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[疟疾中的贫血和血小板减少症。I. 机制]

[Anemia and thrombocytopenia in malaria. I. Mechanisms].

作者信息

Górski J, Nahorski W, Goljan J, Felczak-Korzybska I, Flasiński J

机构信息

Kliniki Chorób Zawodowych i Tropikalnych Instytutu Medycyny Morskiej i Tropikalnej, Gdyni.

出版信息

Przegl Lek. 1994;51(5):221-3.

PMID:7938653
Abstract

Pathomechanism of thrombocytopenia and anaemia which frequently occur in patients with malaria is of a complex origin. Anaemia occurs due to sequestrating, destruction and hemolysis of damaged, parasite infected erythrocytes, as well as of the impaired and ineffective erythropoiesis in the marrow. Thrombocytopenia in these patients may also result from both increased destruction of blood platelets and decreased thrombocytopoiesis. Similar natures of the processes cause that anaemia and thrombocytopenia frequently co-exist in patients with malaria.

摘要

疟疾患者中经常出现的血小板减少症和贫血症的发病机制源于复杂的病因。贫血的发生是由于受损的、被寄生虫感染的红细胞被隔离、破坏和溶血,以及骨髓中红细胞生成受损和无效。这些患者的血小板减少症也可能是由于血小板破坏增加和血小板生成减少所致。这些过程的相似性质导致贫血和血小板减少症在疟疾患者中经常同时存在。

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