Quagliano P V, Hayes C W, Palmer W E
Department of Diagnostic Radiology, Medical College of Virginia, Richmond 23298-0615.
Skeletal Radiol. 1994 Jul;23(5):353-5. doi: 10.1007/BF02416992.
Diffuse idiopathic skeletal hyperostosis is an ossifying diathesis that commonly affects the vertebral skeleton. Spinal ankylosis can occur, predisposing the spine to abnormal stresses and fracture. Fracture through an ankylosed segment with continued motion at the site of fracture can result in pseudoarthrosis. Pseudoarthrosis can also develop at the junction of the fused and mobile spine secondary to chronic abnormal stresses. This complication is manifest radiographically by single-level intervertebral disc space destruction, vertebral endplate erosions, marked vertebral sclerosis, and large osteophytes. The radiographic manifestations can mimic infective spondylitis or neuropathic changes.
弥漫性特发性骨肥厚是一种通常累及脊柱骨骼的骨化素质。可发生脊柱强直，使脊柱易于承受异常应力并发生骨折。骨折穿过强直节段且骨折部位持续活动可导致假关节形成。继发于慢性异常应力时，假关节也可在融合与活动脊柱的交界处发生。这种并发症在影像学上表现为单节段椎间盘间隙破坏、椎体终板侵蚀、明显的椎体硬化和大的骨赘。影像学表现可模拟感染性脊柱炎或神经病变。
