单价和多价竹叶青抗蛇毒血清与不同种类竹叶青（矛头蝮蛇）蛇毒的交叉反应性。
Cross-reactivity of monovalent and polyvalent Trimeresurus antivenoms with venoms from various species of Trimeresurus (lance-headed pit viper) snake.
作者信息
Tan N H, Choy S K, Chin K M, Ponnudurai G
机构信息
Department of Biochemistry, University of Malaya, Kuala Lumpur, Malaysia.
出版信息
Toxicon. 1994 Jul;32(7):849-53. doi: 10.1016/0041-0101(94)90010-8.
Trimeresurus bite is a serious medical problem in Asia. However, at present only a few monospecific Trimeresurus antivenoms are available. Investigation of the cross-neutralization capacity of three Trimeresurus antivenoms indicates that the antivenoms exhibit broad cross-reactivity. A polyvalent Trimeresurus antivenom was also found to be effective in neutralization of the haemorrhagic, necrotizing and thrombin-like activities of heterologous Trimeresurus venoms.
竹叶青蛇咬伤在亚洲是一个严重的医学问题。然而，目前仅有少数几种单特异性竹叶青蛇抗蛇毒血清。对三种竹叶青蛇抗蛇毒血清的交叉中和能力的研究表明，这些抗蛇毒血清具有广泛的交叉反应性。还发现一种多价竹叶青蛇抗蛇毒血清在中和异源竹叶青蛇毒液的出血、坏死和类凝血酶活性方面有效。
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