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60岁以上患者的原位肝移植

Orthotopic liver transplantation in patients over 60 years old.

作者信息

Bromley P N, Hilmi I, Tan K C, Williams R, Potter D

机构信息

Department of Anaesthesia, King's College Hospital, London, United Kingdom.

出版信息

Transplantation. 1994 Oct 15;58(7):800-3.

PMID:7940714
Abstract

A retrospective examination was performed, including a case control study, of 40 patients aged 60 years and over who underwent liver transplantation at King's College Hospital, London, UK, between 1988 and September 1993. There was no significant difference between elderly patients and younger patients in preoperative condition, intraoperative interventions, or outcome assessed by survival, complication rate, and duration of stay on the intensive care unit. The only significant difference between age groups was the median length of hospital stay, which was 24 days for the elderly versus 20 days for younger patients. We conclude that age up to 70 years should not be a barrier to liver transplantation.

摘要

我们对1988年至1993年9月期间在英国伦敦国王学院医院接受肝移植的40名60岁及以上患者进行了回顾性检查,包括病例对照研究。老年患者与年轻患者在术前状况、术中干预或通过生存率、并发症发生率和重症监护病房住院时间评估的结果方面没有显著差异。年龄组之间唯一的显著差异是住院时间中位数,老年患者为24天,而年轻患者为20天。我们得出结论,70岁以下的年龄不应成为肝移植的障碍。

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引用本文的文献

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Transplant of Elderly Patients: Is There an Upper Age Cutoff?老年患者的移植:是否存在上限年龄?
Clin Liver Dis. 2021 Feb;25(1):209-227. doi: 10.1016/j.cld.2020.09.001. Epub 2020 Oct 21.
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Mechanisms and implications of age-related changes in the liver: nonalcoholic Fatty liver disease in the elderly.肝脏中与年龄相关变化的机制及影响:老年人非酒精性脂肪性肝病
Curr Gerontol Geriatr Res. 2011;2011:831536. doi: 10.1155/2011/831536. Epub 2011 Sep 12.
3
Age is not a contraindication for orthotopic liver transplantation: a single institution experience with recipients older than 75 years.
年龄并非原位肝移植的禁忌证:单中心对75岁以上受者的经验
Hepatol Int. 2012 Jan;6(1):403-7. doi: 10.1007/s12072-011-9286-7. Epub 2011 Jun 18.