Duff J P, Chasey D, Munro R, Wooldridge M
Veterinary Investigation Centre, Bury St Edmunds, Suffolk.
Vet Rec. 1994 Jun 25;134(26):669-73. doi: 10.1136/vr.134.26.669.
The livers from 50 brown hares (Lepus europaeus) were examined by electron microscopy for calicivirus-like particles typical of the virus of European brown hare syndrome (EBHS). The virus was visible in 23 of the livers which included four taken from hares which died in 1982 and 1985 and which had been stored at -20 degrees C. The clinical histories, post mortem and other findings associated with these 23 hares were similar to those described in cases of European brown hare syndrome in other European countries. The findings were compared with those associated with viral haemorrhagic disease (VHD) of rabbits which, although it did not occur in the United Kingdom until 1992, is also caused by a calicivirus believed to be related to EBHS virus. The finding of the virus in hares which died from the disease in 1982 is the earliest recorded isolation of the organism and predates the description of VHD virus and VHD in China in 1984. A retrospective review of post mortem reports revealed cases of disease between 1976 and 1977 which may have been due to EBHS and it is considered that the disease has occurred sporadically in England for several years. The results from suspected and confirmed cases of EBHS in England between 1976 and 1990 are reported and the epidemiology and emergence of the disease is considered.
对50只褐兔（欧洲野兔）的肝脏进行了电子显微镜检查，以寻找欧洲野兔综合征（EBHS）病毒特有的杯状病毒样颗粒。在23只肝脏中发现了该病毒，其中包括4只分别于1982年和1985年死亡且保存在-20摄氏度的野兔的肝脏。这23只野兔的临床病史、尸检及其他发现与其他欧洲国家欧洲野兔综合征病例中所描述的情况相似。将这些发现与家兔病毒性出血病（VHD）相关的发现进行了比较，家兔病毒性出血病尽管直到1992年才在英国出现，但也是由一种据信与EBHS病毒有关的杯状病毒引起的。在1982年死于该病的野兔中发现该病毒，这是该病原体有记录以来最早的分离，早于1984年中国对VHD病毒和VHD的描述。对尸检报告的回顾性审查发现，1976年至1977年间可能有因EBHS导致的病例，据认为该病已在英国零星出现数年。报告了1976年至1990年间英国疑似和确诊的EBHS病例的结果，并对该病的流行病学和出现情况进行了分析。
