Peschgens T, Stollbrink-Peschgens C, Merz U, Schneider B, Maurin N, Kutta T, Hörnchen H
Kinderklinik, RWTH Aachen.
Z Geburtshilfe Perinatol. 1994 May-Jun;198(3):96-9.
Primary hyperparathyroidism has to be accused to cause serious morbidity during pregnancy not only on the maternal, but also on the fetal side: the fetus is threatened by prematurity, dystrophy and an increased risk of stillbirth. Postpartually hypocalcaemia and tetany may be observed as the result of neonatal hypoparathyroidism caused by maternal and thus also fetal hypercalcaemia. We report the case of a 32-year-old pregnant woman suffering from a severe form of primary hyperparathyroidism caused by an adenoma of the parathyroidea. The tumor was removed in the 34. week of pregnancy. Six weeks later the patient delivered a healthy boy (birth weight 3450 g). A survey is given of the therapeutical procedures that should be arranged individually by interdisciplinary consulting depending on the degree of maternal disease and on the gestational age.
原发性甲状旁腺功能亢进必须被归咎于在孕期引发严重的发病情况,这不仅体现在母体方面,在胎儿方面也是如此:胎儿受到早产、营养不良以及死产风险增加的威胁。产后低钙血症和手足搐搦可能是由于母体进而胎儿高钙血症导致的新生儿甲状旁腺功能减退所致。我们报告一例32岁患有由甲状旁腺腺瘤引起的严重原发性甲状旁腺功能亢进的孕妇病例。该肿瘤在妊娠34周时被切除。六周后,患者产下一名健康男婴(出生体重3450克)。本文综述了应根据母体疾病程度和孕周通过多学科会诊进行个体化安排的治疗程序。