用一种改良的犬细小病毒活疫苗对具有母源抗体的幼犬进行鼻内接种。
Intranasal vaccination of pups with maternally derived antibodies with a modified live canine parvovirus.
作者信息
Buonavoglia C, Cavalli A, Gravino E, Voigt V, Buonavoglia D, de Caprariis D
机构信息
Istituto di Malattie Infettive e Parassitarie degli Animali, Facoltà di Medicina Veterinaria, Università Bari, Italia.
出版信息
Zentralbl Veterinarmed B. 1994 Mar;41(1):3-8. doi: 10.1111/j.1439-0450.1994.tb00199.x.
Abstract
The modified live canine parvovirus (CPV) vaccine was used to vaccinate intranasally twenty-five pups with maternal antibody. The vaccine was able to overcome the interference of maternal immunity in rates of 100%, 72.7% and 17.6% in pups with haemagglutination inhibition antibody titre of 40, 80 and 160 respectively.
摘要
使用改良的犬细小病毒（CPV）活疫苗对25只具有母源抗体的幼犬进行鼻内接种。对于血凝抑制抗体效价分别为40、80和160的幼犬，该疫苗克服母源免疫干扰的成功率分别为100%、72.7%和17.6%。
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