Ohnishi N, Kishima Y, Hashimoto K, Kiwamoto H, Esa A, Sugiyama T, Park Y C, Kurita T
Department of Urology, Kinki University School of Medicine.
Hinyokika Kiyo. 1994 Aug;40(8):663-7.
Laser-doppler blood flowmetry, a new instrument for measurement of tissue blood flow, was used to evaluate the changes occurring in the bladder blood flow and the intravesical pressure during bladder distension in 4 patients with normal detrusor function, 4 patients with neurogenic bladder dysfunction and one patient with non-neurogenic contracted bladder. In patients with normal detrusor function and normal compliance, the bladder blood flow relatively decreased, but the intravesical pressure was not affected by the bladder distension. On the other hand, the bladder distension in patients with low compliant bladder caused a significant decrease of the bladder blood flow and marked increase of the intravesical pressure. These observations suggest that the reduction of the bladder compliance is related to the decrease of the bladder blood flow. Furthermore, the bladder over distension and the high intravesical pressure in patients with low compliant bladder are thought to induce deterioration of bladder compliance and upper urinary tract.
激光多普勒血流仪是一种用于测量组织血流的新型仪器，用其评估4例逼尿肌功能正常的患者、4例神经源性膀胱功能障碍患者及1例非神经源性膀胱挛缩患者在膀胱扩张期间膀胱血流及膀胱内压的变化。在逼尿肌功能正常且顺应性正常的患者中，膀胱血流相对减少，但膀胱扩张未影响膀胱内压。另一方面，膀胱顺应性低的患者膀胱扩张导致膀胱血流显著减少及膀胱内压明显升高。这些观察结果提示膀胱顺应性降低与膀胱血流减少有关。此外，膀胱顺应性低的患者膀胱过度扩张及高膀胱内压被认为会导致膀胱顺应性及上尿路恶化。
