Odes H S, Locker C, Neumann L, Zirkin H J, Weizman Z, Sperber A D, Fraser G M, Krugliak P, Gaspar N, Eidelman L
Department of Gastroenterology, Soroka Medical Center, Beer-Sheva, Israel.
Am J Gastroenterol. 1994 Oct;89(10):1859-62.
Crohn's disease in Israel was described in the past as being of low incidence, more common in Europe-America-born Jews than other Jews, and of uncharacteristically low morbidity. However, recent experience has suggested that these premises are no longer correct.
The records of all hospital and outpatient cases of Crohn's disease in southern Israel for the period 1968-1992 were reviewed. Private family practitioners and specialists were contacted to assure complete case ascertainment.
The prevalence rate of Crohn's disease among Jews on December 31, 1992, was 50.6/10(5) (Asia-Africa-born Jews 55.0/10(5), Europe-America-born Jews 58.7/10(5), and the rate was 8.2/10(5) among Bedouin Arabs. The annual incidence rate (1987-1992) was calculated as 4.2/10(5)/yr in Jews (Asia-Africa-born 4.6/10(5)/yr, Europe-America-born 3.9/10(5)/yr). The age of presentation declined progressively over the study period, was lower in Israel-born patients than immigrants, and was lower in ileocolonic versus other sites of disease.
The data show that Crohn's disease has become more common in Jews in Israel, losing ethnic differences of frequency, and that it occurs at a younger age than before. In Arabs, the disease is more rare.
过去曾描述以色列的克罗恩病发病率较低，在欧美出生的犹太人中比其他犹太人更常见，且发病率异常低。然而，最近的经验表明这些前提已不再正确。
回顾了1968年至1992年以色列南部所有克罗恩病住院和门诊病例的记录。联系了私人家庭医生和专科医生以确保病例完整确诊。
1992年12月31日，犹太人中克罗恩病的患病率为50.6/10⁵（亚非出生的犹太人为55.0/10⁵，欧美出生的犹太人为58.7/10⁵），贝都因阿拉伯人的患病率为8.2/10⁵。年发病率（1987 - 1992年）在犹太人中计算为4.2/10⁵/年（亚非出生的为4.6/10⁵/年，欧美出生的为3.9/10⁵/年）。在研究期间，发病年龄逐渐下降，在以色列出生的患者中低于移民，在回结肠疾病患者中低于其他疾病部位的患者。
数据表明，克罗恩病在以色列犹太人中变得更为常见，频率上的种族差异消失，且发病年龄比以前更小。在阿拉伯人中，该疾病更为罕见。
