Strandness D E
Department of Surgery, University of Washington School of Medicine, Seattle 98195.
Am J Kidney Dis. 1994 Oct;24(4):674-8. doi: 10.1016/s0272-6386(12)80230-7.
To determine the accuracy of ultrasonic duplex scanning in detecting and classifying renal artery stenosis, we compared the results of duplex scanning with arteriograms in 41 patients with a total of 74 arteries available for comparison. By using a peak systolic velocity of more than 180 cm/s, duplex scanning was able to discriminate between normal and diseased renal arteries with a sensitivity of 95% and a specificity of 90%. Since blood flow velocity across an area of narrowing will increase is roughly proportional to the degree of narrowing, it appeared that the ratio of peak systolic velocity in the area of stenosis to that in the aorta (RAR) of greater than 3.5 predicted the presence of a more than 60% diameter reduction of the renal artery. Using a RAR of 3.5, duplex scanning agreed in 44 renal arteries the sensitivity was 92%. In the 26 renal arteries in which the lesions were less than 60% by arteriography, duplex scanning agreed in 16 arteries and correctly detected an area of focal narrowing in nine of the 10 remaining vessels. Ten of the 11 occluded renal arteries were correctly identified by duplex scanning. Duplex scanning identified the location of the renal artery stenosis with an accuracy of 95%. We believe the data shows that duplex scanning is an accurate method of detecting renal artery stenosis and provides a suitable method of estimating the degree of narrowing.
为了确定超声双功扫描在检测和分级肾动脉狭窄方面的准确性,我们对41例患者共74条可供比较的动脉进行了双功扫描结果与动脉造影结果的比较。通过使用收缩期峰值速度超过180cm/s,双功扫描能够以95%的敏感性和90%的特异性区分正常和病变的肾动脉。由于狭窄区域的血流速度增加与狭窄程度大致成比例,因此狭窄区域的收缩期峰值速度与主动脉的收缩期峰值速度之比(RAR)大于3.5似乎预示着肾动脉直径减少超过60%。使用RAR为3.5时,双功扫描在44条肾动脉中结果相符,敏感性为92%。在动脉造影显示病变小于60%的26条肾动脉中,双功扫描在16条动脉中结果相符,并在其余10条血管中的9条中正确检测到局灶性狭窄区域。11条闭塞性肾动脉中的10条通过双功扫描被正确识别。双功扫描确定肾动脉狭窄位置的准确率为95%。我们认为这些数据表明双功扫描是检测肾动脉狭窄的一种准确方法,并提供了一种估计狭窄程度的合适方法。