Eichler M D, Fraunfelder F T
Department of Ophthalmology, Oregon Health Sciences University, Portland 97201.
Am J Ophthalmol. 1994 Oct 15;118(4):463-7. doi: 10.1016/s0002-9394(14)75797-6.
Lymphoid tumors of the conjunctiva traditionally are treated with radiation therapy. Twelve patients with 42 lymphoid tumors were treated with liquid nitrogen spray and were followed up for 26 to 139 months (mean, 75 months). Twenty-eight (67%) tumors resolved with a single treatment, 39 (93%) with a second treatment, and 41 (98%) with a third treatment. Systemic lymphoma developed in two (17%) of 12 patients. These results are comparable to those with radiation therapy. The results of this case series indicate that cryotherapy for certain conjunctival lymphomatous tumors may be a viable option, because of fewer ocular and systemic complications and lower cost.
结膜淋巴样肿瘤传统上采用放射治疗。12例患有42个淋巴样肿瘤的患者接受了液氮喷雾治疗，并随访了26至139个月（平均75个月）。28个（67%）肿瘤经单次治疗消退，39个（93%）经二次治疗消退，41个（98%）经三次治疗消退。12例患者中有2例（17%）发生了全身性淋巴瘤。这些结果与放射治疗的结果相当。该病例系列结果表明，对于某些结膜淋巴瘤性肿瘤，冷冻疗法可能是一种可行的选择，因为其眼部和全身并发症较少且成本较低。
