Spiers E M, Grotting J C, Omura E F
Department of Dermatology, University of Pennsylvania, Philadelphia.
Am J Dermatopathol. 1994 Jun;16(3):315-9. doi: 10.1097/00000372-199406000-00016.
A variety of local and systemic adverse reactions has been attributed to silicone prostheses used for augmentation or reconstructive mammoplasty. We present a patient who developed an unusual local cutaneous reaction to a silicone breast implant, which was characterized clinically by macular erythema and focal ulceration and histologically by a basaloid proliferative epidermal reaction. The epidermal changes seen histologically simulated those overlying dermatofibromas and were felt to be reactive secondary to silicone leakage and fibrosis. The process resolved postexplantation of the prosthesis.
多种局部和全身不良反应被认为与用于隆胸或乳房重建整形手术的硅胶假体有关。我们报告了一名患者，她对硅胶乳房植入物出现了一种不寻常的局部皮肤反应，临床特征为斑状红斑和局灶性溃疡，组织学特征为基底样增生性表皮反应。组织学上所见的表皮变化类似于覆盖在皮肤纤维瘤上的变化，被认为是硅胶渗漏和纤维化继发的反应性改变。该过程在假体取出后得到缓解。
