Nakagomi O, Isegawa Y, Ward R L, Knowlton D R, Kaga E, Nakagomi T, Ueda S
Department of Microbiology, Akita University School of Medicine, Japan.
Arch Virol. 1994;137(3-4):381-8. doi: 10.1007/BF01309483.
Culture adaptation of rotaviruses from an infant with severe diarrhea in Cincinnati, Ohio, yielded not only a virus with the original RNA electropherotype (CJN) but also rotaviruses with other electropherotypes, the most dominant of which was called CJN-M [Ward RL, Knowlton DR, Schiff GM, Hoshino Y, Greenberg HB (1988) in J Virol 62: 1543-1549]. RNA-RNA hybridization and sequencing studies indicated that CJN was a typical G1P8 human rotavirus while CJN-M was a G1P5 strain and contained four gene segments (including segment 4) of a bovine rotavirus. Thus, the infant was apparently dually infected with human and bovine rotaviruses.
对来自俄亥俄州辛辛那提市一名患有严重腹泻的婴儿的轮状病毒进行培养适应，不仅产生了具有原始RNA电泳图谱（CJN）的病毒，还产生了具有其他电泳图谱的轮状病毒，其中最主要的被称为CJN-M [沃德·RL、诺尔顿·DR、希夫·GM、星野·Y、格林伯格·HB（1988年），《病毒学杂志》62卷：1543 - 1549页]。RNA - RNA杂交和测序研究表明，CJN是一种典型的G1P8人轮状病毒，而CJN-M是一种G1P5毒株，并且包含牛轮状病毒的四个基因片段（包括第4片段）。因此，该婴儿显然同时感染了人轮状病毒和牛轮状病毒。
