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两种新型催眠药唑吡坦和佐匹克隆的筛选、鉴定与测定

Screening, identification and determination of the two new hypnotics zolpidem and zopiclone.

作者信息

Ahrens B, Schütz H, Seno H, Weiler G

机构信息

Institut für Rechtsmedizin, Universität Giessen.

出版信息

Arzneimittelforschung. 1994 Jul;44(7):799-802.

PMID:7945511
Abstract

This article reports basic analytical data for screening and detection of the hypnotics zolpidem (CAS 82626-48-0) and zopiclone (CAS 43200-80-2) by using corrected hR-values, GC (gas chromatography) retention indices, UV solvent spectra and remission spectra. Beside this a HPTLC (high-performance thin-layer chromatography)-procedure for quantification is described.

摘要

本文报道了通过使用校正的hR值、气相色谱(GC)保留指数、紫外溶剂光谱和漫反射光谱对催眠药唑吡坦(CAS 82626-48-0)和佐匹克隆(CAS 43200-80-2)进行筛选和检测的基本分析数据。除此之外,还描述了一种用于定量的高效薄层色谱(HPTLC)方法。

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引用本文的文献

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Clinical pharmacokinetics of zopiclone.
Clin Pharmacokinet. 1995 Dec;29(6):431-41. doi: 10.2165/00003088-199529060-00004.