Law C L, Sidorenko S P, Clark E A
Dept of Microbiology, University of Washington, Seattle 98195.
Immunol Today. 1994 Sep;15(9):442-9. doi: 10.1016/0167-5699(94)90275-5.
Accessory molecules play an important role in the regulation of lymphocyte activation mediated by the B-cell antigen receptor (BCR). CD22 is one such accessory molecule expressed on B-lineage cells. Here, Che-Leung Law and colleagues review current knowledge on the structure-function relationship between CD22 and the BCR, discuss the role of CD22 as a cell-adhesion molecule and suggest models for potential in vivo functions of CD22.
辅助分子在由B细胞抗原受体（BCR）介导的淋巴细胞活化调节中发挥重要作用。CD22就是一种在B淋巴细胞系细胞上表达的辅助分子。在此，罗子亮及其同事综述了关于CD22与BCR之间结构-功能关系的现有知识，讨论了CD22作为细胞黏附分子的作用，并提出了CD22潜在体内功能的模型。
