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[不同炮制方法的草乌与制草乌毒性的实验比较]

[Experimental comparison of the toxicity of radix Aconity Kusnezoffii and processed radix Aconity Kusnezoffii by different methods].

作者信息

Ma C, Cai B c, Cheng L

机构信息

Nanjing College of Traditional Chinese Medicine.

出版信息

Zhongguo Zhong Yao Za Zhi. 1994 Apr;19(4):216-8, 255-6.

PMID:7945852
Abstract

This paper deals with the effects of Radix Aconity Kusnezoffii and Radix Aconity Kusnezoffii processed by a new method of moistening and steaming, and by pharmacopoeial routine on acute toxicity, cardiac rhythm and respiration. The result shows that the Radix Aconity Kusnezoffii processed by new method No 1., which applies moistening in water for 48h and then heating with high pressure steam (68.65kPa, 115 degrees C) for 2h, has the advantages of lower toxicity, and lesser inhibitory effect on cardiac rhythm and respiration.

摘要

本文探讨了新的润蒸方法炮制的草乌及其药典常规炮制法对急性毒性、心律及呼吸的影响。结果表明，新方法1（即水浸润48小时后，再用高压蒸汽（68.65kPa，115℃）加热2小时）炮制的草乌具有毒性较低、对心律及呼吸抑制作用较小的优点。

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