Nash A A, Sunil-Chandra N P
Department of Veterinary Pathology, University of Edinburgh, Summerhall, UK.
Curr Opin Immunol. 1994 Aug;6(4):560-3. doi: 10.1016/0952-7915(94)90141-4.
Our understanding of the host response to gammaherpesviruses comes largely from studies on Epstein-Barr virus. A recent addition to this family is murine herpesvirus-68 which, like Epstein-Barr virus, establishes a latent infection in B lymphocytes and is associated with lymphoproliferative disease. This virus provides a unique opportunity to explore the relationship between gammaherpesviruses and the immune system.
我们对宿主对γ疱疹病毒反应的理解很大程度上来自对爱泼斯坦-巴尔病毒的研究。这个病毒家族最近新增的成员是鼠疱疹病毒68,它与爱泼斯坦-巴尔病毒一样,在B淋巴细胞中建立潜伏感染,并与淋巴增殖性疾病有关。这种病毒为探索γ疱疹病毒与免疫系统之间的关系提供了独特的机会。