小鼠γ疱疹病毒68：γ疱疹病毒发病机制研究的模型
Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis.
作者信息
Simas J P, Efstathiou S
机构信息
Dept of Pathology, University of Cambridge, UK.
出版信息
Trends Microbiol. 1998 Jul;6(7):276-82. doi: 10.1016/s0966-842x(98)01306-7.
PMID:9717216
Abstract
Murine gammaherpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of wild rodents and is genetically related to human herpesvirus 8 and Epstein-Barr virus. The ability of MHV-68 to establish acute and persistent infection within laboratory mice offers a unique opportunity to investigate immunological and virological aspects of gammaherpesvirus pathogenesis.
摘要
小鼠γ-疱疹病毒68（MHV-68）是野生啮齿动物中自然存在的一种疱疹病毒，在基因上与人类疱疹病毒8和爱泼斯坦-巴尔病毒相关。MHV-68在实验小鼠体内建立急性和持续性感染的能力为研究γ-疱疹病毒发病机制的免疫学和病毒学方面提供了独特的机会。
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