Iitaka K, Igarashi S, Sakai T
Department of Paediatrics, Kitasato University School of Medicine, Kanagawa, Japan.
Pediatr Nephrol. 1994 Aug;8(4):420-2. doi: 10.1007/BF00856519.
Yearly screening was performed from 1980 to 1985 in 92,934 school children in the first to ninth grades; a total of 370,148 urine specimens were evaluated. In 1980 and 1981, urinary abnormalities were detected in 0.23% of children examined; the detection rates at the third level of screening for proteinuria, haematuria and haematuria with proteinuria were 0.03%, 0.15% and 0.06%, respectively. The criteria for haematuria were changed from 6 to 20 red blood cells/high power field in the second screening after 1981. Between 1982 and 1985, the equivalent rates were 0.02%, 0.07% and 0.03%, respectively, and the total abnormality prevalence was 0.13%. In 19 children the serum C3 level was below 53 mg/dl; in 5 of these it was below 30 mg/dl. Of these 5 children, 4 underwent renal biopsy and were diagnosed as having membranoproliferative glomerulonephritis.
1980年至1985年期间，对92934名一至九年级的学童进行了年度筛查；共评估了370148份尿液标本。1980年和1981年，在接受检查的儿童中，0.23%检测出尿液异常；蛋白尿、血尿和蛋白尿伴血尿三级筛查的检出率分别为0.03%、0.15%和0.06%。1981年后的第二次筛查中，血尿标准从每高倍视野6个红细胞改为20个红细胞。1982年至1985年期间，相应比率分别为0.02%、0.07%和0.03%，总异常患病率为0.13%。19名儿童的血清C3水平低于53mg/dl；其中5名低于30mg/dl。在这5名儿童中，4名接受了肾活检，被诊断为膜增生性肾小球肾炎。
