Lamey P J, Douglas P S, Napier S S
School of Clinical Dentistry, Queen's Univeristy of Belfast, Northern Ireland.
Br J Oral Maxillofac Surg. 1994 Aug;32(4):214-7. doi: 10.1016/0266-4356(94)90205-4.
A prospective study was undertaken of 100 Sri Lankan patients with oral cancer and an equal number of age and sex matched control individuals. Each subject's secretor status was established from samples of appropriately prepared whole saliva using a haemagglutination technique. No significant differences were recorded in the distribution of secretors or non-secretors between the patient and control groups. In contrast to studies of Caucasians with potentially malignant oral lesions such as candidal leukoplakia in which non-secretor status predominates, secretor status does not appear to be an associated risk marker for the development for oral cancer in a selected Sri Lankan population.
对100名患有口腔癌的斯里兰卡患者以及数量相等、年龄和性别匹配的对照个体进行了一项前瞻性研究。使用血凝技术，从适当制备的全唾液样本中确定了每个受试者的分泌型状态。患者组和对照组之间分泌型或非分泌型的分布没有显著差异。与对白种人潜在恶性口腔病变（如念珠菌性白斑，其中非分泌型状态占主导）的研究相反，在选定的斯里兰卡人群中，分泌型状态似乎不是口腔癌发生的相关风险标志物。
