Bayet M C, Schussler N, Verney C, Peillon F
Unité INSERM 223, Faculté de Médecine Pitié-Salpêtrière, Paris, France.
Neuroreport. 1994 Jul 21;5(12):1505-8. doi: 10.1097/00001756-199407000-00024.
Tyrosine-hydroxylase (TH)-like immunoreactivity was investigated in normal and oestrogenized rat anterior pituitaries in the light of recent studies showing a TH enzymatic activity in the gland and the presence of TH mRNA in endocrine cells. Sparse TH positive fibres, probably dopaminergic as assessed by the absence of dopamine-beta-hydroxylase (DBH) immunoreactivity, were detected in the anterior pituitary, but the detection of TH immunoreactivity in cells was unsuccessful.
鉴于最近的研究表明腺体内存在酪氨酸羟化酶（TH）酶活性以及内分泌细胞中存在TH mRNA，我们对正常和雌激素化大鼠的垂体前叶进行了TH样免疫反应性研究。在垂体前叶检测到稀疏的TH阳性纤维，由于缺乏多巴胺-β-羟化酶（DBH）免疫反应性，推测其可能为多巴胺能纤维，但未成功检测到细胞中的TH免疫反应性。
