Pozniak A L, Weinberg J, Mahari M, Neill P, Houston S, Latif A
Department of Medicine, University of Zimbabwe, Harare.
Tuber Lung Dis. 1994 Aug;75(4):297-300. doi: 10.1016/0962-8479(94)90136-8.
To determine whether tuberculous pericardial effusion is associated with HIV infection.
Retrospective cohort study.
Harare, Zimbabwe.
61 consecutive patients presenting with tuberculous pericarditis over an 18 month period.
Tuberculous pericarditis was significantly associated with HIV seropositivity (odds ratio [OR] 2.46, 95% confidence interval [CI] 1.4-4.3, P = 0.001). The combination of tuberculous pericarditis and tuberculosis at another clinically obvious site (disseminated disease) was more common than pericarditis alone, and was significantly associated with HIV seropositivity (OR 6.1, CI 1.5-25, P = 0.007). Patients with disseminated disease were usually in CDC stage IV prior to the diagnosis of their tuberculosis.
确定结核性心包积液是否与HIV感染有关。
回顾性队列研究。
津巴布韦哈拉雷。
18个月期间连续61例表现为结核性心包炎的患者。
结核性心包炎与HIV血清阳性显著相关(优势比[OR]2.46,95%置信区间[CI]1.4 - 4.3,P = 0.001)。结核性心包炎与另一临床明显部位的结核病(播散性疾病)合并出现比单独的心包炎更常见,且与HIV血清阳性显著相关(OR 6.1,CI 1.5 - 25,P = 0.007)。播散性疾病患者在诊断结核病之前通常处于美国疾病控制与预防中心(CDC)IV期。