Williams H C, Strachan D P
St. John's Institute of Dermatology, St. Thomas' Hospital, London, UK.
Dermatology. 1994;189(3):238-40. doi: 10.1159/000246845.
Some reports have suggested that psoriasis and eczema are seldom found together. Knowledge of disease co-occurrence could lead to improved understanding of shared or opposing pathological mechanisms.
We sought to determine whether psoriasis and eczema could exist simultaneously and consecutively in the same individuals.
Skin examination data relating to 9,263 British children born during March 3rd to 9th, 1958 (the National Child Development Survey), were analysed for the co-occurrence of eczema and psoriasis.
Of 354 children with visible eczema at the ages of 11 or 16 years, 5 (1.4%) were also noted to have visible psoriasis, compared to 89 (1.0%) of 8,909 children who did not have visible eczema at 11 or 16 years. The relative risk of psoriasis in a case of eczema was 1.41, 95% confidence intervals from 0.58 to 3.46.
Contrary to some hospital-based studies which have suggested that the two diseases are seldom found together, this study of a large and representative population suggests that eczema and psoriasis may co-occur concurrently and consecutively in the same individual.
一些报告表明银屑病和湿疹很少同时出现。了解疾病的共现情况有助于更好地理解共同或相反的病理机制。
我们试图确定银屑病和湿疹是否能在同一个体中同时或相继存在。
分析了与1958年3月3日至9日出生的9263名英国儿童（全国儿童发展调查）相关的皮肤检查数据，以确定湿疹和银屑病的共现情况。
在11岁或16岁时有明显湿疹的354名儿童中，有5名（1.4%）也被发现有明显的银屑病，而在11岁或16岁时没有明显湿疹的8909名儿童中有89名（1.0%）患有银屑病。湿疹患者患银屑病的相对风险为1.41，95%置信区间为0.58至3.46。
与一些基于医院的研究表明这两种疾病很少同时出现相反，这项针对大量具有代表性人群的研究表明，湿疹和银屑病可能在同一个体中同时或相继出现。
