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Congenital varicella syndrome: studies of the virus-specific humoral and cell-mediated immune responses.

作者信息

Schuster V, Hofmann G, Pannenbecker J, Kreth H W

机构信息

Department of Paediatrics, University Hospital, Würzburg, Germany.

出版信息

Acta Paediatr. 1994 Jul;83(7):783-5. doi: 10.1111/j.1651-2227.1994.tb13141.x.

DOI:10.1111/j.1651-2227.1994.tb13141.x
PMID:7949816
Abstract

We describe a three-year-old boy with congenital varicella syndrome. Persistent IgG antibodies to varicella-zoster virus (VZV) were detected in the child's sera for a period of more than three years. Immunological studies performed at three months and at three years of age showed a VZV-specific cellular immune response. The results suggest that intrauterine VZV infections in early pregnancy can induce adequate humoral and cellular immune reactions in the infected foetus.

摘要

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