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溃疡性结肠炎中的抗结肠抗体。一项临床研究。

Anti-colon antibodies in ulcerative colitis. A clinical study.

作者信息

Marcussen H

出版信息

Scand J Gastroenterol. 1976;11(8):763-7.

PMID:794998
Abstract

145 consecutively admitted patients with ulcerative colitis were clinically classified. A female:male ratio of 1.46:1 was found. Clinical symptoms and signs presumed to indicate hypersensitivity were present in 30% (95% confidence limits 23-39%). Circulating anti-colon antibodies were found in 20% (95% confidence limits 14-28%) with a female preponderance of 2.63:1. None of the following factors were significantly correlated to the presence of anti-colon antibodies: the age or sex of the patients, the degree of colonic involvement, duration of disease, age of onset, family history of disease, or manifestations of hypersensitivity associated with ulcerative colitis.20

摘要

对145例连续性收治的溃疡性结肠炎患者进行了临床分类。发现男女比例为1.46:1。据推测表明存在超敏反应的临床症状和体征见于30%(95%置信区间为23 - 39%)的患者。20%(95%置信区间为14 - 28%)的患者发现有循环抗结肠抗体,女性优势比例为2.63:1。以下因素均与抗结肠抗体的存在无显著相关性:患者的年龄或性别、结肠受累程度、病程、发病年龄、家族病史或与溃疡性结肠炎相关的超敏反应表现。

相似文献

1
Anti-colon antibodies in ulcerative colitis. A clinical study.溃疡性结肠炎中的抗结肠抗体。一项临床研究。
Scand J Gastroenterol. 1976;11(8):763-7.
2
Circulating antibodies and leucocyte migration inhibition to colon-associated antigen in ulcerative colitis and Crohn's disease.溃疡性结肠炎和克罗恩病中针对结肠相关抗原的循环抗体及白细胞游走抑制作用
Scand J Gastroenterol. 1974;9(2):149-52.
3
Fluorescent anti-colon antibodies and inflammatory eosinophilia in ulcerative colitis.溃疡性结肠炎中的荧光抗结肠抗体与炎性嗜酸性粒细胞增多
Scand J Gastroenterol. 1974;9(6):575-7.
4
Immunological studies in ulcerative colitis. V. Family studies.溃疡性结肠炎的免疫学研究。V. 家族研究。
Gastroenterology. 1971 Mar;60(3):381-9.
5
[Immunohistochemical study of HLA-DR expression in superficial epithelium and in lamina propria of colonic mucosa in children with Crohn's disease and nonspecific ulcerative colitis].[克罗恩病和非特异性溃疡性结肠炎患儿结肠黏膜浅表上皮及固有层中HLA-DR表达的免疫组织化学研究]
Arq Gastroenterol. 1998 Apr-Jun;35(2):143-51.
6
[Clinical importance of organ-specific antibodies in ulcerative colitis and Crohn disease].
Z Gastroenterol. 1992 May;30(5):319-24.
7
[Distribution of cells containing different IgG and IgA subclasses in the colonic mucosa in childhood ulcerative colitis and Crohn disease].[儿童溃疡性结肠炎和克罗恩病结肠黏膜中含不同IgG和IgA亚类细胞的分布]
Orv Hetil. 1991 Sep 15;132(37):2027-31.
8
Immunological studies in ulcerative colitis. VII. Anti-colon antibodies of different immunoglobulin classes.溃疡性结肠炎的免疫学研究。VII. 不同免疫球蛋白类别的抗结肠抗体。
Clin Exp Immunol. 1970 Oct;7(4):469-75.
9
Fluorescent anti-colon and organ-specific antibodies in ulcerative colitis.溃疡性结肠炎中的荧光抗结肠和器官特异性抗体。
Scand J Gastroenterol. 1973;8(1):9-15.
10
Low prevalence of anti-neutrophil cytoplasmic antibodies in ulcerative colitis patients with long-term remission.长期缓解的溃疡性结肠炎患者中抗中性粒细胞胞浆抗体的低患病率。
Eur J Gastroenterol Hepatol. 1995 Jun;7(6):563-8.

引用本文的文献

1
Isolation and characterization of colonic tissue-bound antibodies from patients with idiopathic ulcerative colitis.特发性溃疡性结肠炎患者结肠组织结合抗体的分离与鉴定。
Proc Natl Acad Sci U S A. 1978 Sep;75(9):4528-32. doi: 10.1073/pnas.75.9.4528.