Shmerling M D, Filiushina E E
Morfologiia. 1993 Jul-Aug;105(7-8):90-7.
Albino rats were kept at about 0 degrees C during 42 days. Hepatocytes were found to have greater amount of mitochondria, lysosomes, peroxisomes. Considerable reserves of glycogen were also noted. It speaks of high energetic potential of hepatic cells which may be considered as the most important criterion of cold adaptation. On the other side, signs of decreased protein synthesis in hepatocytes (decreased relative volume of granular endoplasmic reticulum, less number density of ribosomes related to membranes) are thought to be an indication of inhibition of the specific secretory function of the organ which might be "the pay for adaptation" of organism to low temperatures.
白化大鼠在42天内被饲养在约0摄氏度的环境中。发现肝细胞含有更多数量的线粒体、溶酶体和过氧化物酶体。还观察到大量的糖原储备。这表明肝细胞具有很高的能量潜力，这可能被视为冷适应的最重要标准。另一方面，肝细胞中蛋白质合成减少的迹象（颗粒内质网相对体积减小，与膜相关的核糖体数量密度降低）被认为是该器官特定分泌功能受到抑制的表现，这可能是生物体对低温“适应的代价”。
