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不同肿瘤中新鲜肿瘤组织和石蜡包埋肿瘤组织的流式细胞术DNA分析比较

Comparative flow cytometric DNA analysis on fresh and paraffin-embedded tumor tissue in different neoplasms.

作者信息

Niezabitowski A, Lackowska B, Ryś J, Dyba T, Gruchała A, Szklarski W, Stelmach A, Kruczak A, Swiatkiewicz I

机构信息

Department of Tumor Pathology, Center of Oncology, Kraków.

出版信息

Pol J Pathol. 1994;45(3):203-8.

PMID:7953437
Abstract

The results of flow cytometric DNA-analysis on fresh and paraffin-embedded tissue were compared in four various groups of tumors. The best correlation of the results was observed in the group of non Hodgkin's lymphomas. Comparative analysis of the ploidy on fresh and paraffin embedded tissue demonstrated discordance in particular in mammary carcinoma and malignant melanoma groups. The values of proliferative fraction assessed on fresh and paraffin embedded tissues were interrelated.

摘要

在四组不同的肿瘤中,对新鲜组织和石蜡包埋组织进行了流式细胞术DNA分析,并比较了结果。在非霍奇金淋巴瘤组中观察到结果的最佳相关性。对新鲜组织和石蜡包埋组织的倍性进行比较分析发现,特别是在乳腺癌和恶性黑色素瘤组中存在不一致性。在新鲜组织和石蜡包埋组织上评估的增殖分数值是相关的。

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