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1
Differential laminar expression of particulate and soluble guanylate cyclase genes in rat retina.大鼠视网膜中颗粒型和可溶性鸟苷酸环化酶基因的层状差异表达。
Exp Eye Res. 1993 Jan;56(1):51-62. doi: 10.1006/exer.1993.1008.
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Cloning and expression of an ATP-regulated human retina C-type natriuretic factor receptor guanylate cyclase.一种ATP调节的人视网膜C型利钠肽受体鸟苷酸环化酶的克隆与表达
Biochemistry. 1993 Feb 16;32(6):1391-5. doi: 10.1021/bi00057a001.
3
Immunoactive atrial natriuretic peptide in the rat eye: molecular forms in anterior uvea and retina.大鼠眼中的免疫活性心房利钠肽：前葡萄膜和视网膜中的分子形式
Biochem Biophys Res Commun. 1986 Jan 29;134(2):1022-8. doi: 10.1016/s0006-291x(86)80523-x.
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The primary structure of a plasma membrane guanylate cyclase demonstrates diversity within this new receptor family.质膜鸟苷酸环化酶的一级结构在这个新的受体家族中表现出多样性。
Cell. 1989 Sep 22;58(6):1155-62. doi: 10.1016/0092-8674(89)90513-8.
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Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases.心房钠尿肽和脑钠尿肽对两种不同受体鸟苷酸环化酶的差异激活作用。
Nature. 1989 Sep 7;341(6237):68-72. doi: 10.1038/341068a0.
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Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.人心房钠尿肽受体为第二信使信号转导定义了一种新的模式。
EMBO J. 1989 May;8(5):1377-84. doi: 10.1002/j.1460-2075.1989.tb03518.x.
7
The guanylate cyclase/receptor family of proteins.鸟苷酸环化酶/受体蛋白家族
FASEB J. 1989 Jul;3(9):2026-35. doi: 10.1096/fasebj.3.9.2568301.
8
A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor.一种鸟苷酸环化酶的膜形式是心房利钠肽受体。
Nature. 1989 Mar 2;338(6210):78-83. doi: 10.1038/338078a0.
9
Visual excitation and recovery.视觉兴奋与恢复。
J Biol Chem. 1991 Jun 15;266(17):10711-4.
10
Guanylyl cyclase is a heat-stable enterotoxin receptor.鸟苷酸环化酶是一种热稳定肠毒素受体。
Cell. 1990 Nov 30;63(5):941-8. doi: 10.1016/0092-8674(90)90497-3.

人心房钠尿肽受体鸟苷酸环化酶（ANPRA）的mRNA在人视网膜中的表达。

Expression of mRNA for atrial natriuretic peptide receptor guanylate cyclase (ANPRA) in human retina.

作者信息

Pardhasaradhi K, Kutty R K, Gentleman S, Krishna G

机构信息

Section on Drug-Tissue Interaction, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland 20892.

出版信息

Cell Mol Neurobiol. 1994 Feb;14(1):1-7. doi: 10.1007/BF02088585.

DOI:10.1007/BF02088585
PMID:7954658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11566796/
Abstract
  1. Guanylate cyclase plays an important role in the visual cycle. Here we report the mRNA expression for the atrial natriuretic peptide receptor type A form of guanylate cyclase (ANPRA) in human retina. 2. Polymerase chain reaction using two sets of primers on the cDNAs reverse-transcribed from human retinal poly(A)+ RNA amplified two products under two different reaction conditions. The primers used in the reaction were designed from the reported sequence of human placental ANPRA cDNA. 3. Sequencing of the amplified products showed 100% sequence homology to the human placental ANPRA gene. Northern blot analysis indicated the presence of a 4.4-kb ANPRA mRNA in human retina, similar to that present in human brain.
摘要
  1. 鸟苷酸环化酶在视觉循环中起重要作用。在此，我们报告人视网膜中鸟苷酸环化酶A型心房利钠肽受体（ANPRA）的mRNA表达。2. 使用两组引物对从人视网膜poly(A)+ RNA逆转录得到的cDNA进行聚合酶链反应，在两种不同反应条件下扩增出两种产物。反应中使用的引物是根据已报道的人胎盘ANPRA cDNA序列设计的。3. 扩增产物的测序显示与人类胎盘ANPRA基因具有100%的序列同源性。Northern印迹分析表明人视网膜中存在4.4 kb的ANPRA mRNA，与人类大脑中的相似。