人心房钠尿肽受体鸟苷酸环化酶（ANPRA）的mRNA在人视网膜中的表达。
Expression of mRNA for atrial natriuretic peptide receptor guanylate cyclase (ANPRA) in human retina.
作者信息
Pardhasaradhi K, Kutty R K, Gentleman S, Krishna G
机构信息
Section on Drug-Tissue Interaction, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland 20892.
出版信息
Cell Mol Neurobiol. 1994 Feb;14(1):1-7. doi: 10.1007/BF02088585.
Abstract
- Guanylate cyclase plays an important role in the visual cycle. Here we report the mRNA expression for the atrial natriuretic peptide receptor type A form of guanylate cyclase (ANPRA) in human retina. 2. Polymerase chain reaction using two sets of primers on the cDNAs reverse-transcribed from human retinal poly(A)+ RNA amplified two products under two different reaction conditions. The primers used in the reaction were designed from the reported sequence of human placental ANPRA cDNA. 3. Sequencing of the amplified products showed 100% sequence homology to the human placental ANPRA gene. Northern blot analysis indicated the presence of a 4.4-kb ANPRA mRNA in human retina, similar to that present in human brain.
摘要
- 鸟苷酸环化酶在视觉循环中起重要作用。在此，我们报告人视网膜中鸟苷酸环化酶A型心房利钠肽受体（ANPRA）的mRNA表达。2. 使用两组引物对从人视网膜poly(A)+ RNA逆转录得到的cDNA进行聚合酶链反应，在两种不同反应条件下扩增出两种产物。反应中使用的引物是根据已报道的人胎盘ANPRA cDNA序列设计的。3. 扩增产物的测序显示与人类胎盘ANPRA基因具有100%的序列同源性。Northern印迹分析表明人视网膜中存在4.4 kb的ANPRA mRNA，与人类大脑中的相似。
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2
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