津巴布韦的新生儿血液学。I：血小板参数。

Neonatal haematology in Zimbabwe. I: The platelet parameters.

作者信息

Mukiibi J M, Nkrumah F K, Kaur M, Akino V, Nhembe M

机构信息

Department of Haematology, University of Zimbabwe Medical School, Avondale, Harare.

出版信息

Cent Afr J Med. 1994 Apr;40(4):80-3.

PMID:7954714

Abstract

Platelet parameters were determined in 600 full term healthy Zimbabwean neonates using a Coulter Counter Model S Plus. The mean +/- s.d. values obtained with ranges were: Platelet count 235 +/- 67 (range 100-410) x 10(9) l-1; Mean Platelet Volume (MPV) 9.5 +/- 1.0 (range 7.1-13.9) fl; Plateletcrit (PCT) 0.269 +/- 0.058 (range 0.142-0.524) and Platelet Distribution Width (PDW) 16.8 +/- 1.0 (range 12.2-19.8). Although platelet counts in this study were comparable to those established by others in both Black and Caucasian infants, the female Zimbabwean neonates had significantly higher counts than the males (p < 0.001). An inverse relationship between the number of circulating platelets and their MPV was also observed. Further studies are needed to delineate the range of normality of these platelet measurements in the African neonate so that abnormal cases can be adequately screened, investigated and appropriately treated.

摘要

使用库尔特S Plus型号血细胞计数器对600名足月健康的津巴布韦新生儿进行血小板参数测定。获得的平均值±标准差及范围如下：血小板计数235±67（范围100 - 410）×10⁹/L；平均血小板体积（MPV）9.5±1.0（范围7.1 - 13.9）fl；血小板压积（PCT）0.269±0.058（范围0.142 - 0.524）；血小板分布宽度（PDW）16.8±1.0（范围12.2 - 19.8）。尽管本研究中的血小板计数与其他针对黑人及白人婴儿所确定的计数相当，但津巴布韦女性新生儿的血小板计数显著高于男性（p < 0.001）。还观察到循环血小板数量与其MPV之间呈负相关。需要进一步研究来确定非洲新生儿这些血小板测量值的正常范围，以便能够对异常病例进行充分筛查、调查并给予适当治疗。