Patrick C H, Lazarchick J, Stubbs T, Pittard W B
Am J Pediatr Hematol Oncol. 1987 Summer;9(2):130-2. doi: 10.1097/00043426-198722000-00002.
Normal values for mean platelet volume (MPV) and platelet distribution width (PDW) have not been firmly established for term and preterm neonates. Cord blood samples from 143 healthy newborns (78 full term and 65 premature) were analyzed with the Coulter counter. Platelet count and MPV were significantly greater (p less than 0.05 and p less than 0.001, respectively) in term versus preterm infants, while PDW was significantly less in term infants (p less than 0.001). Platelet count and MPV correlated with gestational age, and platelet count also correlated with birth weight. There was a significant (p less than 0.001) negative correlation of PDW with gestational age and birth weight. These data represent normal reference ranges for neonates and demonstrate significant variation with gestational age.
足月和早产新生儿的平均血小板体积（MPV）和血小板分布宽度（PDW）的正常数值尚未完全确定。使用库尔特计数器对143例健康新生儿（78例足月和65例早产）的脐带血样本进行了分析。与早产儿相比，足月儿的血小板计数和MPV显著更高（分别为p<0.05和p<0.001），而足月儿的PDW显著更低（p<0.001）。血小板计数和MPV与胎龄相关，血小板计数也与出生体重相关。PDW与胎龄和出生体重呈显著负相关（p<0.001）。这些数据代表了新生儿的正常参考范围，并显示出随胎龄的显著变化。
