Chow M S, Sim E, Orszulak T A, Schaff H V
Section of Cardiovascular Surgery, Mayo Clinic, Rochester, MN 55905.
Circulation. 1994 Nov;90(5 Pt 2):II129-32.
The early and late patency of the left internal thoracic artery (LITA) has been studied thoroughly, but less is known about coronary artery bypass grafts constructed from the right internal thoracic artery (RITA).
Between January 1984 and March 1991, 413 patients on two surgical services had bilateral arteries or RITAs used as conduits for coronary artery revascularization. Sixty-seven patients (16%; 57 male and 10 female; mean age, 59 years) had graft angiography performed up to 97 months after operation (average, 27 months). In 38 patients, angiography was performed because of angina or other objective evidence of myocardial ischemia. For all 67 patients evaluated, patency of RITA grafts was 86% (58/67), and patency of LITA grafts was 89% (57/64). For grafts to the left anterior descending (LAD) coronary artery, overall patency was 90% (58/64), and there was little difference in patency of the RITA (93%, 28/30) versus the LITA (88%, 30/34). In contrast, the overall patency rate for internal thoracic arteries used to bypass vessels other than the LAD was 76% (45/59, P < .03 versus LAD); for these bypasses to arteries other than the LAD, RITA patency was 74% (26/35), and the patency of LITA grafts was 79% (19/24). Patency of RITA grafts routed through the transverse sinus was similar to patency of other bypasses to non-LAD vessels. Among 12 free grafts that used segments of the RITA, 10 were patent (83%). Of additional saphenous vein grafts, 69% (39/56) were patent at restudy.
This study supports the continued use of the RITA as a conduit for coronary artery revascularization. In our experience, the position of the target vessel is a more important determinant of graft patency than the side of the internal thoracic artery selected for use as a bypass graft.
左乳内动脉(LITA)的早期和晚期通畅情况已得到充分研究,但对于由右乳内动脉(RITA)构建的冠状动脉旁路移植术了解较少。
在1984年1月至1991年3月期间,两个手术科室的413例患者接受了双侧动脉或RITA作为冠状动脉血运重建的血管移植物。67例患者(16%;57例男性和10例女性;平均年龄59岁)在术后长达97个月(平均27个月)接受了移植血管造影。38例患者因心绞痛或其他心肌缺血的客观证据而进行了血管造影。在所有67例接受评估的患者中,RITA移植物的通畅率为86%(58/67),LITA移植物的通畅率为89%(57/64)。对于左前降支(LAD)冠状动脉的移植物,总体通畅率为90%(58/64),RITA(93%,28/30)与LITA(88%,30/34)的通畅率差异不大。相比之下,用于绕过LAD以外血管的乳内动脉总体通畅率为76%(45/59,与LAD相比P < 0.03);对于这些绕过LAD以外动脉的移植,RITA通畅率为74%(26/35),LITA移植物的通畅率为79%(19/24)。经横窦的RITA移植物通畅率与其他绕过非LAD血管的移植相似。在12例使用RITA节段的游离移植物中,10例通畅(83%)。在再次检查时,额外的大隐静脉移植物通畅率为69%(39/56)。
本研究支持继续使用RITA作为冠状动脉血运重建的血管移植物。根据我们的经验,靶血管的位置比选择作为旁路移植物的乳内动脉的侧别对移植物通畅性更具重要决定作用。