Cutrona A F, Rothschild B M
Northeastern Ohio University College of Medicine, Western Reserve Care System, Youngstown.
Compr Ther. 1994;20(8):445-58.
The diagnosis of parasitic infections depends on a high level of suspicion after a thorough history and physical examination, mindful of relapsing course of long incubation periods (Table 6). Obvious information that alerts one to the diagnosis include recent travel abroad and in endemic areas of the United States. Within this framework, the most important element in the pursuit of parasitosis is persistence on the part of the physician. Advice from infectious disease specialists and laboratory personnel will increase the probability of finding, identifying, and the treating the underlying process. Serologic tests are helpful in this process. Antigen detection of antibody complexes formation by ELISA technique facilitates specific diagnosis (Table 7). The most important primary care issue is prevention. Treatment with unfamiliar drugs is best pursued with infectious disease consultation because these can have significant toxicities (Table 8). Office announcements reminding patients to ask about travel prophylaxis several months in advance of proposed travel and provision of information concerning endemic parasitoses is recommended.
寄生虫感染的诊断取决于在全面的病史和体格检查后保持高度怀疑,同时要注意到长潜伏期的复发过程(表6)。提示诊断的明显信息包括近期出国旅行以及在美国的流行地区旅行。在此框架内,医生的坚持不懈是追查寄生虫病的最重要因素。传染病专家和实验室人员的建议将增加发现、识别和治疗潜在病症的可能性。血清学检测在这一过程中很有帮助。通过ELISA技术检测抗体复合物形成的抗原有助于进行特异性诊断(表7)。最重要的初级保健问题是预防。最好在传染病会诊的情况下使用不熟悉的药物进行治疗,因为这些药物可能有显著的毒性(表8)。建议在办公室发布公告,提醒患者在计划旅行前几个月询问旅行预防措施,并提供有关地方性寄生虫病的信息。