Pasquale S A, Knuppel R A, Owens A G, Bachmann G A
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903.
Contraception. 1994 Aug;50(2):109-16. doi: 10.1016/0010-7824(94)90047-7.
Seventy-five women with a mean age of 27.5 years who requested Norplant implants for contraception were studied over a five-year period. The patients kept daily diaries of their vaginal bleeding and coital frequency, and were seen at least every six months at which time their weight was measured. This study examines the impact of Norplant implants use on menstrual regularity, body mass index and coital frequency. Irregular bleeding was most prevalent during the first two years of Norplant implants use and accounted for the primary reason for discontinuation of this method. No increase in Body Mass Index (BMI) was noted in Norplant implants users over the five-year study period. Women with irregular bleeding did not have a higher or lower BMI compared to women with regular bleeding and irregular bleeding patterns did not impact on coital frequency. Over five years, four pregnancies occurred during Norplant implant use. Norplant implants are a highly effective contraceptive method and women using this method should not expect an increase in body weight. Irregular bleeding is most frequent during the first two years of use and menstrual cyclicity resumes in the majority of women by the third year of use and continues to the fifth year of use.
对75名平均年龄为27.5岁、要求植入诺普兰皮下避孕埋植剂的女性进行了为期五年的研究。患者每天记录阴道出血情况和性交频率，并且至少每六个月接受一次检查，届时测量她们的体重。本研究考察了使用诺普兰皮下避孕埋植剂对月经规律、体重指数和性交频率的影响。不规则出血在使用诺普兰皮下避孕埋植剂的头两年最为普遍，也是停用该方法的主要原因。在为期五年的研究期间，使用诺普兰皮下避孕埋植剂的女性体重指数没有增加。与月经规律的女性相比，不规则出血的女性体重指数并没有更高或更低，而且不规则出血模式对性交频率没有影响。在使用诺普兰皮下避孕埋植剂的五年期间，发生了4次妊娠。诺普兰皮下避孕埋植剂是一种高效的避孕方法，使用这种方法的女性体重不应增加。不规则出血在使用的头两年最为常见，大多数女性在使用的第三年月经周期恢复正常，并持续到使用的第五年。
