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停用诺普兰二代皮下植入剂后生育能力的恢复。国际医学研究理事会激素避孕特别工作组。

Return of fertility following discontinuation of Norplant-II subdermal implants. ICMR Task Force on Hormonal Contraception.

作者信息

Buckshee K, Chatterjee P, Dhall G I, Hazra M N, Kodkany B S, Lalitha K, Logambal A, Manchanda P, Nanda U K, RaiChoudhury G

机构信息

Division of Human Resource Development Research, Indian Council of Medical Research, Ansari Nagar, New Delhi.

出版信息

Contraception. 1995 Apr;51(4):237-42. doi: 10.1016/0010-7824(95)00039-d.

DOI:10.1016/0010-7824(95)00039-d
PMID:7796589
Abstract

A total of 627 women who had discontinued the use of the Norplant-II implants for various reasons and were exposed to the risk of pregnancy were followed-up for two years for return of fertility. The cumulative conception rates in women who had discontinued due to planning pregnancy were 80.3 per 100 women at one year and 88.3 per 100 women at two years. The majority of women who did conceive (90 percent), had full-term normal live births; about 4 percent of women had spontaneous abortions, the remaining 6 percent decided on elective termination of pregnancy (ETP). The cumulative conception rates in women who discontinued due to bleeding irregularities and 'other reasons' were 64.5 and 55.8 per 100 women at one year and 77.9 and 75.1 per 100 women at two years, respectively. These rates were significantly lower as compared to those observed in women who discontinued due to planning pregnancy. A large proportion, about 40 percent, of women who conceived after discontinuation of the method due to bleeding irregularities and "other reasons," opted for ETP indicating that many women in these two groups did not desire another child and that such women need to be counselled for adopting another method of contraception. The spontaneous abortion rates observed in ex-users of Norplant-II implants (1.7 to 4.4% pregnancies) were comparable to the spontaneous abortion rates prior to Norplant-II implant use (3.6% pregnancies) indicating that ex-users of Norplant-II implants were not at a higher risk of spontaneous abortion.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

共有627名因各种原因停用诺普兰二代植入剂并面临怀孕风险的女性接受了为期两年的生育恢复随访。因计划怀孕而停用的女性,其一年时的累积受孕率为每100名女性中有80.3例,两年时为每100名女性中有88.3例。大多数受孕女性(90%)顺产下足月正常活产婴儿;约4%的女性自然流产,其余6%决定选择人工流产(ETP)。因出血不规律和“其他原因”而停用的女性,其一年时的累积受孕率分别为每100名女性中有64.5例和55.8例,两年时为每100名女性中有77.9例和75.1例。与因计划怀孕而停用的女性相比,这些比率显著较低。很大一部分(约40%)因出血不规律和“其他原因”停用该方法后受孕的女性选择了人工流产,这表明这两组中的许多女性不想要另一个孩子,并且需要为这些女性提供咨询,以便她们采用另一种避孕方法。诺普兰二代植入剂停用者的自然流产率(怀孕的1.7%至4.4%)与使用诺普兰二代植入剂之前的自然流产率(怀孕的3.6%)相当,这表明诺普兰二代植入剂停用者的自然流产风险并不更高。(摘要截断于250字)

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