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Localization of the human melanocortin-5 receptor gene (MC5R) to chromosome band 18p11.2 by fluorescence in situ hybridization.

作者信息

Chowdhary B P, Gustavsson I, Wikberg J E, Chhajlani V

机构信息

Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala.

出版信息

Cytogenet Cell Genet. 1995;68(1-2):79-81. doi: 10.1159/000133895.

DOI:10.1159/000133895
PMID:7956366
Abstract

The recently cloned novel MC5R gene is suggested to be a mediator of neural functions of the melanocortic peptides, such as melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). We now report the localization of the human MC5R locus to chromosome 18p11.2.

摘要

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3
γ₂-Melanocyte stimulation hormone (γ₂-MSH) truncation studies results in the cautionary note that γ₂-MSH is not selective for the mouse MC3R over the mouse MC5R.
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