Goldberg H L
Kauai Community Mental Health Center, University of Hawaii.
Int J Psychiatry Med. 1994;24(2):129-47. doi: 10.2190/2BF1-0718-WE7F-A9F7.
This article reviews the literature on the use of psychotropic drugs in pregnancy and lactation.
Medline search yielded more than five hundred titles. Articles were reviewed and ninety-one were selected for reference.
Fetal physiology and teratogenicity are discussed and the effects of specific drugs on the fetus and newborn are presented. When possible, recommendations for use or non-use are presented.
Though no controlled studies have ever been done in pregnant women to truly prove their safety, it appears that most, but not all, current psychotropic drugs appear fairly safe for use in pregnancy.
本文综述了关于孕期及哺乳期使用精神药物的文献。
通过医学文献数据库检索得到五百多篇文献标题。对这些文章进行了综述,并挑选出91篇作为参考文献。
讨论了胎儿生理学和致畸性,并介绍了特定药物对胎儿和新生儿的影响。尽可能给出了使用或不使用的建议。
尽管从未在孕妇中进行过对照研究以真正证明其安全性,但目前大多数(并非全部)精神药物在孕期使用似乎相当安全。