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毛滴虫苷局部治疗导致人毛囊中环磷酸腺苷(cAMP)水平升高。

Increased cAMP levels in human hair follicles due to local treatment with trichoriboside.

作者信息

Gazzani G, Roncoroni S, Corsi M, Falchi M, Ferrero M E

机构信息

Crinos s.p.a., Villa Guardia, Como, Italy.

出版信息

Int J Tissue React. 1994;16(2):73-7.

PMID:7960503
Abstract

Local therapy with trichoriboside and trichosaccharide, which have been found to be beneficial for scalp hair maintenance in adult males affected by androgenic alopecia, was found to increase cAMP levels in human scalp hair follicles. The increase was significant in men affected by androgenic alopecia, whereas it was not significant in unaffected control men. Trichoriboside showed a greater activity than trichosaccharide, and such activity was accompanied by a significant concomitant reduction of ATP in the hair.

摘要

已发现对受雄激素性脱发影响的成年男性的头皮毛发维持有益的三羟甲基氨基甲烷核糖苷和三羟甲基氨基甲烷糖的局部治疗,可增加人头皮毛囊中的环磷酸腺苷(cAMP)水平。在受雄激素性脱发影响的男性中这种增加是显著的,而在未受影响的对照男性中则不显著。三羟甲基氨基甲烷核糖苷显示出比三羟甲基氨基甲烷糖更大的活性,并且这种活性伴随着毛发中三磷酸腺苷(ATP)的显著同时减少。

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