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RU486:一种备受关注的化合物。

RU486: a compound that gets itself talked about.

作者信息

Baulieu E E

机构信息

Institut National de la Santé et de la Recherche Médicale, Unité 33, Le Kremlin-Bicêtre, France.

出版信息

Hum Reprod. 1994 Jun;9 Suppl 1:1-6. doi: 10.1093/humrep/9.suppl_1.1.

Abstract

In part, RU486 is 'the pill' awaited for centuries by women in difficulty and still threatened by the danger of botched abortions in many countries. This is enough for it to be the object of innumerable articles in the professional and lay press, and of so many private and public debates. The recently demonstrated possibility of stopping the development of pregnancy with a convenient combination of RU486 and a cheap, safe, orally active prostaglandin, and thus the potential of defusing in part the abortion issue, has again headed the front pages of the news. The 'political chemistry' of RU486 (Hogden, 1991), which is still in full swing, delays its introduction and its use by women in need, particularly in the developing world, and by patients suffering from a number of diseases potentially treatable by the drug.

摘要

在一定程度上,RU486就是那些身处困境的女性期待了几个世纪的“药丸”,而在许多国家,它仍然受到堕胎失败危险的威胁。仅凭这一点,它就成为了专业和大众媒体无数文章的主题,引发了诸多私人和公开的辩论。最近证明,将RU486与一种廉价、安全、口服有效的前列腺素方便地联合使用,就有可能终止妊娠的发展,从而在一定程度上化解堕胎问题,这一消息再次登上了新闻头条。RU486的“政治化学”(霍格登,1991年)仍在全力进行,这延缓了它的推广以及有需要的女性,特别是发展中世界的女性,还有患有一些可能可用该药治疗的疾病的患者对它的使用。

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