Ohnishi K, Nagai Y, Okada K, Ishikawa O, Miyachi Y
Department of Dermatology, Gunma University School of Medicine, Japan.
J Dermatol. 1994 Aug;21(8):586-9. doi: 10.1111/j.1346-8138.1994.tb01798.x.
We report the first Japanese patient with primary cutaneous histoplasmosis who was infected inside Japan. He was not an immunocompromised host but his cutaneous lesions developed on preexisting papuloerythroderma (Ofuji). The long-term topical corticosteroid treatment for papuloerythroderma, which could have suppressed the local immunological defence system of the skin, might have been responsible for the histoplasma infection in the present case.
我们报告了首例在日本国内感染原发性皮肤组织胞浆菌病的日本患者。他并非免疫功能低下宿主，但其皮肤病变发生于先前存在的红皮病性丘疹（Ofuji病）基础上。针对红皮病性丘疹的长期局部皮质类固醇治疗可能抑制了皮肤局部免疫防御系统，这可能是本例中组织胞浆菌感染的原因。
