Pritchard C W
Public Health Research Unit, Glasgow.
J Epidemiol Community Health. 1994 Aug;48(4):377-82. doi: 10.1136/jech.48.4.377.
The aim was to examine the association between depressive symptoms and smoking in pregnancy and to investigate the part played by social and psychosocial factors.
A single Glasgow hospital.
Prospective survey by postal questionnaires at 20 and 30 weeks' gestation.
A total of 395 women (69% of the 572 eligible) parity 1 who booked for delivery between November 1988 and February 1990 took part.
Depressive symptoms were measured using the Hospital Anxiety and Depression Scale. Smoking was self reported. The Life Events Inventory and measures of role specific strain and stress in domestic roles were used to assess psychosocial well being.
Smokers were more likely than non-smokers to experience depressive symptoms at 20 and 30 weeks' gestation and on both occasions. The excess risk remained substantial and significant after adjustment for social and psychosocial factors.
Smoking is a significant risk factor for depression in pregnancy. The association of smoking with depression and psychosocial difficulty represents a major problem for interventions intended to reduce smoking in pregnancy.
研究孕期抑郁症状与吸烟之间的关联，并调查社会和心理社会因素所起的作用。
格拉斯哥的一家医院。
在妊娠20周和30周时通过邮寄问卷进行前瞻性调查。
共有395名单胎初产妇（占572名符合条件者的69%）参与，她们于1988年11月至1990年2月期间登记分娩。
使用医院焦虑抑郁量表测量抑郁症状。吸烟情况由产妇自行报告。采用生活事件量表以及家庭角色中特定角色紧张和压力的测量方法来评估心理社会幸福感。
吸烟者在妊娠20周和30周时以及这两个时间点都比不吸烟者更易出现抑郁症状。在对社会和心理社会因素进行调整后，额外风险仍然很大且具有统计学意义。
吸烟是孕期抑郁的一个重要危险因素。吸烟与抑郁及心理社会问题之间的关联对于旨在减少孕期吸烟的干预措施而言是一个重大问题。
