Strukov A I, Vorob'eva A A
Kardiologiia. 1976 Nov;16(11):8-17.
This paper presents an analysis of publications, mostly by Soviet authores, on clinical studies and morphological examinations of the microcirculatory bed in different pathology. It is concluded that the microcirculatory bed should be regarded as an integral system responding to the pathological effects by a local and general reaction of its structural components and by changing the rheological properties of blood. Two types of changes develop in the microcirculatory system -- sterotyped ones, typical for extreme states (various kinds of shock, hypertensive crisis, stress situations), and those specific for certain diseases (diabetes melitus, essential hypertension, athersclerosis, collagenoses, etc.). In all the above diseases the pathological process affects the functional structures of microcirculation that undergo a rearrangement in accordance with the requirements of the body. In the initial period of the disease this re-arrangement is of a compensatory nature and passes ahead of the clinical manifestations. A comparison of the pictutrs obtained by biomicroscopy of the bulbconjunctiva of the eye and of other mucosae with film preparations of the serosae demonstrates their complete similarity. Therefore, the method of biomicroscopy of the eyeball and of the mucosae as a method reflecting the state of microcirculation in the body as a whole should become an integral part of the clinical examination of patients.
本文对主要由苏联作者撰写的关于不同病理状态下微循环床的临床研究和形态学检查的出版物进行了分析。得出的结论是，应将微循环床视为一个整体系统，它通过其结构成分的局部和全身反应以及改变血液的流变学特性来应对病理影响。微循环系统会出现两种类型的变化——定型变化，这是极端状态（各种休克、高血压危象、应激情况）所特有的；以及特定疾病（糖尿病、原发性高血压、动脉粥样硬化、胶原病等）所特有的变化。在上述所有疾病中，病理过程会影响微循环的功能结构，这些结构会根据身体的需求进行重新排列。在疾病的初期，这种重新排列具有代偿性质，且先于临床表现出现。通过对眼球球结膜和其他黏膜的生物显微镜检查所获得的图像与浆膜的薄膜制剂进行比较，发现它们完全相似。因此，眼球和黏膜的生物显微镜检查方法作为一种反映全身微循环状态的方法，应成为患者临床检查的一个组成部分。
