Chen R, Novick A C, Pohl M
Department of Urology, Cleveland Clinic Foundation, Ohio 44195.
J Urol. 1995 Jan;153(1):133-4. doi: 10.1097/00005392-199501000-00047.
We report on a patient with severe hypertension and nephrotic range proteinuria, which were renin mediated in origin. Aortography demonstrated occlusion of the right renal artery and renal vein renin measurements lateralized strongly to the right kidney. Removal of the right kidney led to amelioration of hypertension and proteinuria. Massive proteinuria in this setting is due to high levels of intrarenal angiotensin II and is reversible with deactivation of the renin-angiotensin system.
我们报告了一名患有严重高血压和肾病范围蛋白尿的患者，其病因是肾素介导的。主动脉造影显示右肾动脉闭塞，肾静脉肾素测量结果强烈偏向右侧肾脏。切除右肾后，高血压和蛋白尿得到改善。在这种情况下，大量蛋白尿是由于肾内血管紧张素II水平升高所致，并且通过肾素-血管紧张素系统失活是可逆的。
