Günalp I, Gündüz K, Dürük K, Kanpolat Y
Department of Ophthalmology, Faculty of Medicine, University of Ankara, Turkey.
Jpn J Ophthalmol. 1994;38(2):185-90.
Fifty-three patients with neurogenic orbital tumors were diagnosed and treated at our university hospital during the past three decades. There were 16 patients with juvenile pilocytic astrocytomas, 21 patients with meningiomas and 16 with peripheral nerve tumors. Of the 16 peripheral nerve tumor patients, 8 had schwannoma, 4 had neurofibroma, 2 had malignant schwannoma, one had paraganglioma and one had amputation neuroma. Optic nerve tumors were treated via a transfrontal craniotomy if there was no chiasmal involvement. Cases with chiasmal involvement, incomplete resections and recurrences were treated with radiotherapy (5000 cGy). Far advanced cases with progressive proptosis and ocular damage underwent exenteration. Peripheral nerve tumors were treated by local resection. Exenteration was applied when there was an advanced or malignant lesion. Four of the 16 glioma patients and 5 of the 21 meningioma patients died during follow-up. The prognosis for peripheral nerve tumors was generally good, except for malignant schwannomas. Two patients with this malignant tumor died within 2 years after surgery.
在过去三十年中，我校附属医院共诊断并治疗了53例神经源性眼眶肿瘤患者。其中有16例青少年毛细胞型星形细胞瘤患者，21例脑膜瘤患者和16例周围神经肿瘤患者。在16例周围神经肿瘤患者中，8例为神经鞘瘤，4例为神经纤维瘤，2例为恶性神经鞘瘤，1例为副神经节瘤，1例为截肢神经瘤。如果没有视交叉受累，视神经肿瘤通过经额开颅手术治疗。视交叉受累、切除不完全和复发的病例采用放射治疗（5000 cGy）。病情进展严重、眼球突出且眼部受损的晚期病例接受眶内容剜除术。周围神经肿瘤采用局部切除术治疗。当存在晚期或恶性病变时进行眶内容剜除术。16例胶质瘤患者中有4例和21例脑膜瘤患者中有5例在随访期间死亡。除恶性神经鞘瘤外，周围神经肿瘤的预后总体良好。两名患有这种恶性肿瘤的患者在手术后两年内死亡。
