von Hartitzsch B, Kerr D N
Nephron. 1976;17(6):430-8. doi: 10.1159/000180751.
The effects of intravenous iron, with and without androgens, was studied in a group of 39 patients treated by regular haemodialysis, almost all of whom had normal serum iron concentrations. Intravenous iron 1-2 g every 4 months produced a significant rise in haemoglobin from 6.3 to 7.9 g/dl in 17 female patients with their kidneys in situ (p less than 0.001). In a group of 13 male subjects intravenous iron plus testosterone produced a similar rise in haemoglobin from 6.9 to 8.6 g/dl (p less than 0.001). Nine nephrectomised patients showed no significant response to iron and androgens. There were no fatalities and no serious side effects in 500 courses of intravenous iron.
对一组39例接受常规血液透析治疗的患者研究了静脉注射铁剂（无论是否联合雄激素）的效果，这些患者几乎所有人血清铁浓度均正常。17例肾脏原位的女性患者每4个月静脉注射1 - 2 g铁剂后，血红蛋白从6.3 g/dl显著升至7.9 g/dl（p<0.001）。在一组13例男性受试者中，静脉注射铁剂加睾酮使血红蛋白从6.9 g/dl升至8.6 g/dl，情况类似（p<0.001）。9例肾切除患者对铁剂和雄激素无明显反应。500个疗程的静脉注射铁剂治疗中无死亡病例，也无严重副作用。
