Pekrun A, Schiffmann H, Lakomek M
Universitäts-Kinderklinik Göttingen.
Klin Padiatr. 1994 Jul-Aug;206(4):346-8. doi: 10.1055/s-2008-1046628.
A 3 years old patient receiving chemotherapy for acute-lymphoblastic leukemia according to the ALL-BFM 90-treatment protocol developed thrombosis of the vena axillaris. Without removing the central venous catheter located at the site of thrombosis it was possible to lyse the thrombus by the systemic application of recombinant human tissue-type plasminogen activator (rt-PA). The method is recommended for the treatment of thrombotic occlusions in children.
一名3岁急性淋巴细胞白血病患者按照ALL-BFM 90治疗方案接受化疗，发生了腋静脉血栓形成。在不取出位于血栓部位的中心静脉导管的情况下，通过全身应用重组人组织型纤溶酶原激活剂（rt-PA）成功溶解了血栓。该方法推荐用于儿童血栓性闭塞的治疗。
