Mróz E, Podolak-Dawidziak M, Grzybek-Hryncewicz K, Dworniczek E
Katedra i Zakład Mikrobiologii AM we Wrocławiu.
Med Dosw Mikrobiol. 1994;46(1-2):5-8.
The study involved 412 strains of Gram-positive cocci isolated from throat, sputum, urine and stool of patients prepared for bone marrow transplantation at Department of Hematology. Determination of drug susceptibility was performed by disc diffusion method applying discs with roxithromycin, erythromycin, lincomycin, clindamycin and augmentin. Among strains of S. aureus, S. epidermidis and Micrococcus susceptible strains comprised respectively 48, 48 and 45%; among group A, B, C and G streptococci respectively 92 and 52%. Among 108 strains of group D Streptococci only 24% were susceptible to roxithromycin. Comparison of susceptibility of tested strains to roxithromycin and other antibiotics revealed similar susceptibility of staphylococci and streptococci to roxithromycin and erythromycin, while among staphylococci higher percentage of strains and among streptococci lower percentage was susceptible to lincomycin than to roxithromycin.
该研究纳入了412株革兰氏阳性球菌，这些菌株分离自血液学系准备进行骨髓移植的患者的咽喉、痰液、尿液和粪便。采用含罗红霉素、红霉素、林可霉素、克林霉素和阿莫西林克拉维酸钾的药敏纸片，通过纸片扩散法进行药敏测定。在金黄色葡萄球菌、表皮葡萄球菌和微球菌菌株中，敏感菌株分别占48%、48%和45%；在A、B、C和G组链球菌中，敏感菌株分别占92%和52%。在108株D组链球菌中，只有24%对罗红霉素敏感。受试菌株对罗红霉素和其他抗生素的药敏比较显示，葡萄球菌和链球菌对罗红霉素和红霉素的敏感性相似，而在葡萄球菌中，对林可霉素敏感的菌株百分比高于罗红霉素，在链球菌中则低于罗红霉素。
