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[儿童尿路感染中的细菌菌群及药物敏感性]

[Bacterial flora in urinary tract infections of children and susceptibility to drugs].

作者信息

Pawluch D, Szozda G, Nowakowska K, Drejewicz H

机构信息

Zakład Immunologii Instytutu Matki i Dziecka w Warszawie.

出版信息

Med Dosw Mikrobiol. 1994;46(1-2):67-71.

PMID:7967933
Abstract

The material consisted of 902 strains isolated from children with urinary tract infection with significant bacteriuria. Among isolated strains, Enterobacteriaceae consisted 67.4%, Gram-positive cocci 18.8% and non-fermenting Gram-negative bacilli (both against Gram-negative bacilli and Gram-positive cocci), appeared aminoglycosides and III generation cephalosporins (from 63 to 83% of susceptible strains). K. pneumoniae and P. aeruginosa were most resistant to antimicrobials tested. The authors point out that empiric antibiotic therapy of bacterial urinary tract infections in children which is not preceded by identification of the pathogen and determination of its drug susceptibility, can be ineffective in over 50% of cases.

摘要

该材料由从患有显著菌尿的尿路感染儿童中分离出的902株菌株组成。在分离出的菌株中,肠杆菌科占67.4%,革兰氏阳性球菌占18.8%,非发酵革兰氏阴性杆菌(针对革兰氏阴性杆菌和革兰氏阳性球菌)对氨基糖苷类和第三代头孢菌素呈现出敏感性(敏感菌株占63%至83%)。肺炎克雷伯菌和铜绿假单胞菌对所测试的抗菌药物耐药性最强。作者指出,在未对病原体进行鉴定及其药敏测定之前就对儿童细菌性尿路感染进行经验性抗生素治疗,在超过50%的病例中可能无效。

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