[食管癌的外科治疗——早期结果]

[Surgical therapy of esophageal cancer--early results].

作者信息

Hildebrandt J, Nürnberger H, Lehner J, Löhlein D

机构信息

Chirurgische Klinik, Städtischen Kliniken Dortmund.

出版信息

Med Klin (Munich). 1994 Sep 15;89(9):459-63.

PMID:7968879

Abstract

PATIENTS AND METHOD

A prospective study was undertaken in 230 patients with carcinoma of the esophagus and of the cardia with infiltration of the distal oesophageal part from 1988 to 1993.

RESULTS

According to postoperative UICC-classification 3% of patients had stage 0, 43% stage I/II and 54% stage III/IV. 162/230 were resected (resection rate 70.4%). 55% (89/162) of resected patients had thoracoabdominocervical, 38% (62) thoracoabdominal and 8% (11) transhiatal esophagectomy. Rate of anastomotic break-down was 1.9% (3/162). Clinical mortality decreased from 32% in 1988/89 to 11% in 1990/91 to at least 0% in 1992/93 (total 13%).

CONCLUSION

Control of the postoperative phase is of decisive importance in decreasing mortality after esophageal resection, while surgical-technical problems seem to be solved. Esophagectomy is possible even as palliative measure in the presence of low mortality.

摘要

患者与方法

1988年至1993年，对230例食管及贲门癌伴食管远端浸润的患者进行了一项前瞻性研究。

结果

根据术后UICC分类，3%的患者为0期，43%为I/II期，54%为III/IV期。230例中有162例接受了切除（切除率70.4%）。接受切除的患者中，55%（89/162）行胸腹颈段食管切除术，38%（62例）行胸腹段食管切除术，8%（11例）行经裂孔食管切除术。吻合口破裂率为1.9%（3/162）。临床死亡率从1988/89年的32%降至1990/91年的11%，至1992/93年至少降至0%（总计13%）。