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结节病患者外周血淋巴细胞亚群的评估。

Estimation of lymphocyte subpopulations in the peripheral blood of patients with sarcoidosis.

作者信息

Sorensen S F, Hardt F, Veien N K

出版信息

Scand J Immunol. 1976;5(10):1117-22. doi: 10.1111/j.1365-3083.1976.tb00252.x.

DOI:10.1111/j.1365-3083.1976.tb00252.x
PMID:796971
Abstract

Lymphocyte subpopulations in the peripheral blood of 36 sarcoidosis patients and 36 age- and sex-matched controls were determined, using the sheep erythrocyte rosette (SRBC-R) technique and immunofluorescence staining with whole rabbit anti-human immunoglobulin antisera. In the patient group the total number of lymphocytes, SRBC-R lymphocytes, and IgM-positive lymphocytes was reduced in comparison to in the control group. In the patient group no correlation could be found between any of the lymphocyte subpopulations and disease stage, cutaneous involvement of the disease, or cutaneous reactivity to purified protein derivative and dinitrochlorobenzene.

摘要

采用绵羊红细胞玫瑰花结(SRBC-R)技术及兔抗人免疫球蛋白抗血清免疫荧光染色法,对36例结节病患者及36例年龄和性别相匹配的对照者外周血中的淋巴细胞亚群进行了测定。与对照组相比,患者组淋巴细胞总数、SRBC-R淋巴细胞及IgM阳性淋巴细胞数量均减少。在患者组中,未发现任何淋巴细胞亚群与疾病分期、疾病的皮肤受累情况或对纯化蛋白衍生物和二硝基氯苯的皮肤反应性之间存在相关性。

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1
Estimation of lymphocyte subpopulations in the peripheral blood of patients with sarcoidosis.结节病患者外周血淋巴细胞亚群的评估。
Scand J Immunol. 1976;5(10):1117-22. doi: 10.1111/j.1365-3083.1976.tb00252.x.
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1
Immunocompetent cells and delayed hypersensitivity reaction in sarcoidosis.
Lung. 1981;159(3):137-44. doi: 10.1007/BF02713909.
2
Pulmonary sarcoidosis: assessment of disease activity by lung lymphocyte subpopulations.肺结节病:通过肺淋巴细胞亚群评估疾病活动度。
Klin Wochenschr. 1983 Apr 1;61(7):349-56. doi: 10.1007/BF01485026.