Young R R
Department of Neurology, University of California, Irvine 92717-4275.
Neurology. 1994 Nov;44(11 Suppl 9):S12-20.
This symposium is concerned with the treatment of spasticity and, in particular, with results from studies of tizanidine as a treatment for patients with MS and spinal cord injury. In this article, the definitions and pathophysiologies of spasticity are reviewed, and the issue of when and if to treat spasticity is evaluated. The merits of newer pharmacologic and invasive therapies are discussed relative to reduction of patient discomfort and the possibility of restored function.
本次研讨会关注痉挛的治疗，尤其是替扎尼定治疗多发性硬化症和脊髓损伤患者的研究结果。本文回顾了痉挛的定义和病理生理学，并评估了何时以及是否应治疗痉挛的问题。讨论了新型药物治疗和侵入性治疗在减轻患者不适以及恢复功能可能性方面的优点。
